Thymus Extracellular Matrix-Derived Scaffolds Support Graft-Resident Thymopoiesis and Long-Term In Vitro Culture of Adult Thymic Epithelial Cells

The thymus offers the physiological microenvironment important for the event of T lymphocytes, the cells that orchestrate the adaptive immune system to generate an antigen-specific response. A various inhabitants of stroma cells offers surface-bound and soluble molecules that orchestrate the intrathymic maturation and collection of growing T cells. Forming an intricate 3D structure, thymic epithelial […]