Pharmaceutical and biotechnology firms hardly ever disclose their use of translational rising security biomarkers (ESBs) throughout drug improvement, and the affect of ESB use on the velocity of drug improvement stays unclear. A cross-industry survey of 20 firms of various measurement was performed to know present tendencies in ESB use and future use prospects. The goals had been to: (1) decide present ESB use in nonclinical and medical drug improvement and affect on asset development; (2) determine alternatives, gaps, and challenges to higher ESB implementation; and (3) benchmark views on regulatory acceptance.
Though ESBs had been employed in solely 5-50% of research/packages, most firms used ESBs to some extent, with bigger firms demonstrating higher nonclinical use. Inclusion of ESBs in investigational new drug purposes (INDs) was comparable throughout all firms; nevertheless, variations in medical trial utilization may differ among the many prevailing well being authority (HA). This consists of producing adequate foundational knowledge, demonstrating nonclinical to medical translatability and sensible utility, and clearly written standards by HAs to allow qualification. If achieved, ESBs will play a essential function within the improvement of next-generation, translationally-tailored normal laboratory assessments for drug improvement.
The Committee on the Medical Utility of Cardiac Biomarkers (C-CB) of the Worldwide Federation of Medical Chemistry (IFCC) represents worldwide teams from laboratory medication, cardiology and emergency medication concerned in offering world academic steering pertaining to the analytical and medical purposes of cardiac biomarkers. For that motive, a lot of the members are concerned with nationwide and worldwide research and trials pertaining to excessive sensitivity (hs) cardiac troponins I and T (cTnI and cTnT) (1-3).
Though the just lately printed ‘2020 European Society of Cardiology (ESC) pointers for the administration of acute coronary syndromes in sufferers presenting with out persistent ST-segment elevation’ current some matters very properly, the present particular report was developed to delineate our particular considerations relating to the ESB steering for the usage of hs-cardiac troponin. Broader implementation of ESBs requires useful resource help, cross-industry partnerships, and collaboration with HAs.
Characterization of Steady and Reactive Metabolites of the Anticancer Drug, Ensartinib, in Human Liver Microsomes Utilizing LC-MS/MS: An in silico and Sensible Bioactivation Method
Ensartinib (ESB) is a novel anaplastic lymphoma kinase inhibitor (ALK) with extra exercise in opposition to Abelson murine leukemia (ABL), met proto-oncogene (MET), receptor tyrosine kinase (AXL), and v-ros UR2 sarcoma virus oncogene homolog 1 (ROS1) and is taken into account a safer different for different ALK inhibitors. ESB chemical construction accommodates a dichloro-fluorophenyl ring and cyclic tertiary amine rings (piperazine) that may be bioactivated producing reactive intermediates.
In vitro metabolic examine of ESB with human liver microsomes (HLMs) was carried out and the speculation of producing reactive intermediates throughout metabolism was examined using trapping brokers to seize and stabilize reactive intermediates to facilitate their LC-MS/MS detection. These findings lay the foundations for added work on ESB toxicity. Substituents to the bioactive facilities (piperazine ring), both for blocking or isosteric substitute, would possible block or interrupt hydroxylation response that may finish the bioactivation sequence.
Decreased glutathione (GSH) and potassium cyanide (KCN) had been utilized as trapping brokers for quinone methide and iminium intermediates, respectively. 4 in vitro ESB part I metabolites had been characterised. Three reactive intermediates together with one epoxide and one iminium intermediates had been characterised. ESB bioactivation is proposed to happen by surprising metabolic pathways. The piperazine ring was bioactivated by iminium ions intermediates era, whereas the dichloro-phenyl group was bioactivated by a particular mechanism that was revealed by LC-MS/MS.
Investigating the Evolution and Growth of Organic Techniques from the Perspective of Thermo-Kinetics and Techniques Principle
Life itself is grander than the sum of its constituent molecules. Any residing organism could also be considered part of a dissipative course of that connects irreversible power consumption with development, replica, and evolution. Below energy-fuelled, far-from-equilibrium situations, chemical methods able to exponential development can manifest a particular type of stability- dynamic kinetic stability (DKS) – indicating the persistence of self-reproducible entities. This kinetic conduct is related to thermodynamic situations removed from equilibrium resulting in an evolutionary view of the origin of life by which growing entities must be related to the dissipation of free power.
This evaluation goals to reformulate Darwinian principle in physicochemical phrases in order that it may well deal with each animate and inanimate methods, thus serving to to beat this theoretical divide. The expanded formulation relies on the precept of dynamic kinetic stability and proof from the rising discipline of methods chemistry. Though the basic Darwinian principle is beneficial for understanding the origins and evolution of species, it isn’t meant to primarily construct an specific framework for predicting potential evolution routes.
All through the final century, the inherently systemic and dynamic nature of the organic methods has been dropped at the eye of researchers. Over the last a long time, “methods” approaches to biology and genome evolution are gaining ever higher significance offering the opportunity of a deeper interpretation of the essential ideas of life.
Mitomycin C, 5mg |
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| R5007-5mg | ACTGene | each | EUR 270 |
SynaptoRed C1: (5mg) |
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| 70040 | Biotium | 5MG | EUR 333.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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SynaptoGreen C3: (5mg) |
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| 70023 | Biotium | 5MG | EUR 333.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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SynaptoGreen C5: (5mg) |
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| 70046 | Biotium | 5MG | EUR 333.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Rhodamine-DHPE: (5mg) |
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| 60026 | Biotium | 5MG | EUR 271.2 |
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Description: Minimum order quantity: 1 unit of 5MG |
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SynaptoGreenTM C1: (5mg) |
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| 70042 | Biotium | 5MG | EUR 333.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Fluorescein-DHPE: (5mg) |
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| 60024 | Biotium | 5MG | EUR 271.2 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Biotin-X-DHPE: (5mg) |
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| 60023 | Biotium | 5MG | EUR 284.4 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Arachidonic Acid 5mg/ml |
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| ABP-ARA-1 | Abpcorp | 3 x 0,5ml vials | EUR 68.4 |
Nystatin Solution, 5mg/mL |
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| 41410012-1 | Bio-WORLD | 10 mL | EUR 24.65 |
Amersham Cy5 Maleimide 5mg |
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| PA15130 | Scientific Laboratory Supplies | EACH | EUR 1237.2 |
Linear Polyacrylamide (5mg/ml) |
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| S143 | GeneOn | 1 ml | EUR 48 |
Aminooxy-5(6)-ROX: (5mg) |
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| 90104 | Biotium | 5MG | EUR 290.4 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Phosphate Test 0.5-5mg/L |
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| WAT3653 | Scientific Laboratory Supplies | EACH | EUR 213.7 |
5-TAMRA-PEO3-amine: (5mg) |
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| 90107 | Biotium | 5MG | EUR 446.4 |
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Description: Minimum order quantity: 1 unit of 5MG |
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PNPP sodium salt, 5mg tablets |
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| GX3711-100EA | Glentham Life Sciences | 100 EA | EUR 302.4 |
PNPP sodium salt, 5mg tablets |
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| GX3711-100 | Glentham Life Sciences | 100 | EUR 219.7 |
Phosphorus Reactive 0-5mg/L |
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| WAT1036 | Scientific Laboratory Supplies | EACH | EUR 96 |
DMNPE-Caged D-Luciferin: (5mg) |
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| 10103 | Biotium | 5MG | EUR 177.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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BD fibronectin human plasma 5mg |
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| 356008 | Scientific Laboratory Supplies | EACH | EUR 548.4 |
Biotin-X-C5-maleimide: (5mg) |
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| 90058 | Biotium | 5MG | EUR 225.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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neo PRP MPlate Pop Plate 5mg |
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| CHR5938 | Scientific Laboratory Supplies | EACH | EUR 325.2 |
neo PCX MPlate Pop Plate 5mg |
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| CHR5946 | Scientific Laboratory Supplies | EACH | EUR 334.8 |
Amersham Cy3 Bis NHS ester 5mg |
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| PA13000 | Scientific Laboratory Supplies | EACH | EUR 1315.2 |
Amersham Cy5 Bis NHS ester 5mg |
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| PA15000 | Scientific Laboratory Supplies | EACH | EUR 1293.6 |
Amersham Cy7 Bis NHS ester 5mg |
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| PA17000 | Scientific Laboratory Supplies | EACH | EUR 1315.2 |
Amersham Cy3 Mono NHS ester 5mg |
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| PA13105 | Scientific Laboratory Supplies | EACH | EUR 1310.4 |
Amersham Cy5 mono NHS ester 5mg |
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| PA15100 | Scientific Laboratory Supplies | EACH | EUR 1542 |
Amersham Cy5.5 mono NHS ester 5mg |
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| PA15605 | Scientific Laboratory Supplies | EACH | EUR 1237.2 |
Amersham Cy7 mono NHS ester 5mg |
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| PA17105 | Scientific Laboratory Supplies | EACH | EUR 1297.2 |
5(6)-CR110-C5-Maleimide: (5mg) |
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| 91029 | Biotium | 5MG | EUR 501.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Free Chlorine Reagents 0-5mg/L |
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| WAT1028 | Scientific Laboratory Supplies | EACH | EUR 44.4 |
Albumin Standard Ampules (5mg / ml BSA) |
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| abx090645-1ml | Abbexa | 1 ml | EUR 210 |
5-CR110-PEO4-Propionate, SE:5mg |
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| 90081 | Biotium | 5MG | EUR 574.8 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Chlorine Indicator Strips 0-5mg/L |
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| PAP1226 | Scientific Laboratory Supplies | PK100 | EUR 24 |
Linear Poly Acrylamide Solution (5mg/ml) |
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| LK548 | Bio Basic | 1ml | EUR 75.66 |
3,3-Diaminobenzidine (DAB) 5mg Substrate Tabs |
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| CH027 | ABM | 50 Tabs | EUR 212.4 |
3,3-Diaminobenzidine (DAB) 5mg Substrate Tabs |
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| CH028 | ABM | 100 Tabs | EUR 279.6 |
Adenine Hemisulfate Solution, 5mg/mL, Sterile |
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| 40120711-1 | Bio-WORLD | 50 mL | EUR 26.54 |
Adenine Hemisulfate Solution, 5mg/mL, Sterile |
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| 40120711-2 | Bio-WORLD | 100 mL | EUR 33.86 |
Biotin-PEO4-Propionate Succinimidyl ester: (5mg) |
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| 90069 | Biotium | 5MG | EUR 207.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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BioMag® Dextran-coated Charcoal (5mg/ml) |
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| 84510-100 | Polysciences Europe GmbH | 100ml | EUR 647 |
5-(and-6)-Carboxyrhodamine 6G, hydrochloride, 5mg |
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| 90120 | Biotium | 1MG | EUR 113 |
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Description: N/A |
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5-carboxytetramethylrhodamine, SE (5-TAMRA, SE): (5mg) |
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| 90034 | Biotium | 5MG | EUR 276 |
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Description: Minimum order quantity: 1 unit of 5MG |
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6-carboxytetramethylrhodamine, SE (6-TAMRA, SE): (5mg) |
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| 90035 | Biotium | 5MG | EUR 276 |
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Description: Minimum order quantity: 1 unit of 5MG |
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5-Carboxyrhodamine 6G, hydrochloride, single isomer: (5mg) |
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| 90012 | Biotium | 5MG | EUR 182.4 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Recombinant Multi Species Buserelin Protein, Untagged, -5mg |
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| QP11214-5mg | EnQuireBio | 5mg | EUR 392.4 |
Spectropho Std Mn 5mg/L in 5% HNO3 |
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| OPS-MN5-500 | Scientific Laboratory Supplies | 500ML | EUR 199.76 |
Dispase Solution, 5mg/ml in DMEM/F-12 |
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| CA192-020 | GenDepot | 200 ml | EUR 448.8 |
SynaptoRed C2M (also known as FM5-95): (5mg) |
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| 70028 | Biotium | 5MG | EUR 416.4 |
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Description: Minimum order quantity: 1 unit of 5MG |
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SynaptoGreen C2 (also known asl FM2-10): (5mg) |
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| 70044 | Biotium | 5MG | EUR 333.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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SynaptoGreen C18 (also known as FM3-25): (5mg) |
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| 70048 | Biotium | 5MG | EUR 481.2 |
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Description: Minimum order quantity: 1 unit of 5MG |
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AGLink® ADC Conjugation Kit (MMAE, DAR4, 5mg) |
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| ADC-P003 | ACROBIOSYSTEMS | 1Reaction | EUR 5403.5 |
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Description: Antibody-drug conjugates (ADC) is a type of fast growing anticancer drug. Monoclonal antibody is conjugated to the cytotoxic payload via a chemical linker that directed toward a target antigen expressed on the cancer cell surface, reducing systemic exposure and therefore toxicity. AGLink® ADC conjugation kit is designed to conjugate mAb with toxic payload (MMAE) though site-specific enzymatic reaction. |
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Bovine Type I Collagen Neutralized Solution 5mg/mL |
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| IBOCLGMI35ML | Innovative research | each | EUR 468 |
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Description: Bovine Type I Collagen Neutralized Solution 5mg/mL |
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AGLink® ADC Conjugation Kit (MMAE, DAR2&DAR4, 5mg) |
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| ADC-P004 | ACROBIOSYSTEMS | 1Reaction | EUR 5403.5 |
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Description: Antibody-drug conjugates (ADC) is a type of fast growing anticancer drug. Monoclonal antibody is conjugated to the cytotoxic payload via a chemical linker that directed toward a target antigen expressed on the cancer cell surface, reducing systemic exposure and therefore toxicity. AGLink® ADC conjugation kit is designed to conjugate mAb with toxic payload (MMAE) though site-specific enzymatic reaction. |
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Sulforhodamine 101-PEO3-amine (Texas Red-PEO3-amine): (5mg) |
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| 90110 | Biotium | 5MG | EUR 446.4 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Biotin-X NTA (Biotin-X nitrilotriacetic acid, tripotassium salt): (5mg) |
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| 90056 | Biotium | 5MG | EUR 190.8 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Tetramethylrhodamine-5-isothiocyanate isomer G (5-TRITC, G isomer): (5mg) |
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| 90018 | Biotium | 5MG | EUR 255.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
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Tetramethylrhodamine-6-isothiocyanate isomer R (6-TRITC, R isomer): (5mg) |
|||
| 90019 | Biotium | 5MG | EUR 255.6 |
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Description: Minimum order quantity: 1 unit of 5MG |
|||
MTS-CR110 (MTS-5-(and-6)-carboxyrhodamine 110, mixed isomers): (5mg) |
|||
| 91035 | Biotium | 5MG | EUR 277.2 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
Biotin NTA (biotin nitrilotriacetic acid, tripotassium salt; also called BNTA): (5mg) |
|||
| 90074 | Biotium | 5MG | EUR 190.8 |
|
Description: Minimum order quantity: 1 unit of 5MG |
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Recombinant Rabbit TNC Protein, Untagged, Rabbit-5mg |
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| QP13765-5mg | EnQuireBio | 5mg | EUR 740.4 |
Recombinant Human Leptin Protein, Untagged, E.coli-5mg |
|||
| QP5350-5mg | EnQuireBio | 5mg | EUR 381.6 |
Recombinant Mouse Leptin Protein, Untagged, E.coli-5mg |
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| QP5429-5mg | EnQuireBio | 5mg | EUR 675.6 |
Recombinant Rat Leptin Protein, Untagged, E.coli-5mg |
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| QP5507-5mg | EnQuireBio | 5mg | EUR 643.2 |
Recombinant other Histrelin Protein, Untagged, E.coli-5mg |
|||
| QP12236-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant Human Leuprorelin Protein, Untagged, E.coli-5mg |
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| QP12555-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant other Lypressin Protein, Untagged, E.coli-5mg |
|||
| QP12608-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant other Urease Protein, Untagged, E.coli-5mg |
|||
| QP10907-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant other Antide Protein, Untagged, E.coli-5mg |
|||
| QP11028-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant other Bivalirudin Protein, Untagged, E.coli-5mg |
|||
| QP11165-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant Salmon Calcitonin Protein, Untagged, E.coli-5mg |
|||
| QP11261-5mg | EnQuireBio | 5mg | EUR 469.2 |
Recombinant other MOG Protein, Untagged, E.coli-5mg |
|||
| QP12717-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant Human OCT Protein, Untagged, E.coli-5mg |
|||
| QP12920-5mg | EnQuireBio | 5mg | EUR 337.2 |
Recombinant Human OT Protein, Untagged, E.coli-5mg |
|||
| QP12937-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant other Pramlintide Protein, Untagged, E.coli-5mg |
|||
| QP13132-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant Human Secretin Protein, Untagged, E.coli-5mg |
|||
| QP13449-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant Human SERPINA1 Protein, Untagged, E.coli-5mg |
|||
| QP13455-5mg | EnQuireBio | 5mg | EUR 914.4 |
Recombinant other Sincalide Protein, Untagged, E.coli-5mg |
|||
| QP13506-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant other Eledoisin Protein, Untagged, E.coli-5mg |
|||
| QP11778-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant Human Eptifibatide Protein, Untagged, E.coli-5mg |
|||
| QP11802-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant other Goserelin Protein, Untagged, E.coli-5mg |
|||
| QP12027-5mg | EnQuireBio | 5mg | EUR 175.2 |
Recombinant Human CRP Protein, Untagged, E.coli-5mg |
|||
| QP11513-5mg | EnQuireBio | 5mg | EUR 1698 |
Recombinant other DDAVP Protein, Untagged, E.coli-5mg |
|||
| QP11607-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant other Deslorelin Protein, Untagged, E.coli-5mg |
|||
| QP11661-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant Human EDN3 Protein, Untagged, E.coli-5mg |
|||
| QP11747-5mg | EnQuireBio | 5mg | EUR 1665.6 |
Recombinant Human GHRH Protein, Untagged, E.coli-5mg |
|||
| QP10643-5mg | EnQuireBio | 5mg | EUR 555.6 |
Recombinant Yeast IDH1 Protein, Untagged, Yeast-5mg |
|||
| QP10670-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant Mouse Leptin Protein, Untagged, E.coli-5mg |
|||
| QP10756-5mg | EnQuireBio | 5mg | EUR 620.4 |
Recombinant other Lysostaphin Protein, Untagged, E.coli-5mg |
|||
| QP10778-5mg | EnQuireBio | 5mg | EUR 316.8 |
5-(and-6)-Carboxyrhodamine 110-X, hydrochloride (5(6)-CR 110-X):5mg |
|||
| 90001 | Biotium | 5MG | EUR 339.6 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
5-(and-6)-Carboxyrhodamine 110-X, hydrochloride (5(6)-CR 110-X):5mg |
|||
| 90002 | Biotium | 5MG | EUR 260.4 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
MTS-CR110-X (MTS-5-(and-6)-carboxyrhodamine 110-X, mixed isomers): (5mg) |
|||
| 91036 | Biotium | 5MG | EUR 310.8 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
Dilinoleyl DiO (FAST DiO, or 1, 1'-dilinoleyl-3, 3'-oxacarbocyanine perchlorate): (5mg) |
|||
| 60035 | Biotium | 5MG | EUR 316.8 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
Recombinant other Thymosin ?1 Protein, Untagged, E.coli-5mg |
|||
| QP13745-5mg | EnQuireBio | 5mg | EUR 729.6 |
Recombinant Multi Species Trp Protein, Untagged, E.coli-5mg |
|||
| QP13821-5mg | EnQuireBio | 5mg | EUR 195.6 |
Recombinant Human Urokinase Protein, Untagged, Native Protein-5mg |
|||
| QP13908-5mg | EnQuireBio | 5mg | EUR 675.6 |
Recombinant Multi Species Vasopressin Protein, Untagged, E.coli-5mg |
|||
| QP13923-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant Human Thrombin Protein, Untagged, Native Protein-5mg |
|||
| QP10880-5mg | EnQuireBio | 5mg | EUR 4027.2 |
Recombinant Human Trypsin-2 Protein, Untagged, E.coli-5mg |
|||
| QP10899-5mg | EnQuireBio | 5mg | EUR 241.2 |
Recombinant Human UTI Protein, Untagged, Native Protein-5mg |
|||
| QP10909-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant Human APOH Protein, Untagged, Native Protein-5mg |
|||
| QP11054-5mg | EnQuireBio | 5mg | EUR 4027.2 |
Recombinant other Streptavidin Protein, Untagged, Native Protein-5mg |
|||
| QP13625-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant Human GHRP 2 Protein, Untagged, E.coli-5mg |
|||
| QP11968-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant other GHRP 6 Protein, Untagged, E.coli-5mg |
|||
| QP11969-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant Bovine ECGS Protein, Untagged, Native Protein-5mg |
|||
| QP11736-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant Human EDN2 Protein, Untagged, Native Protein-5mg |
|||
| QP11746-5mg | EnQuireBio | 5mg | EUR 708 |
Recombinant other Avidin Protein, Untagged, Native Protein-5mg |
|||
| QP10525-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant Rat Carboxypeptidase B Protein, Untagged, E.coli-5mg |
|||
| QP10544-5mg | EnQuireBio | 5mg | EUR 186 |
Recombinant other hCG Protein, Untagged, Native Protein-5mg |
|||
| QP10664-5mg | EnQuireBio | 5mg | EUR 218.4 |
Recombinant Human MG Protein, Untagged, Native Protein-5mg |
|||
| QP10785-5mg | EnQuireBio | 5mg | EUR 392.4 |
5-SFX (6-(fluorescein-5-carboxamido)hexanoic acid, succinimidyl ester (single isomer):5mg |
|||
| 90095 | Biotium | 5MG | EUR 199.2 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
6-SFX (6-(fluorescein-6-carboxamido)hexanoic acid, succinimidyl ester (single isomer):5mg |
|||
| 90096 | Biotium | 5MG | EUR 199.2 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
Recombinant Human IGF1 Isoform 2 Protein, Untagged, E.coli-5mg |
|||
| QP5005-5mg | EnQuireBio | 5mg | EUR 1546.8 |
Recombinant Human IGF1 Isoform 2 Protein, Untagged, E.coli-5mg |
|||
| QP10392-ec-5mg | EnQuireBio | 5mg | EUR 381.6 |
Recombinant Bovine Alkaline Phosphatase Protein, Untagged, Native Protein-5mg |
|||
| QP10518-5mg | EnQuireBio | 5mg | EUR 316.8 |
Nestin (Cancer Stem Cell Marker)(NES/2911), 0.2mg/mL |
|||
| BNUB2911-100 | Biotium | 1uL | EUR 225 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), 0.2mg/mL |
|||
| BNUB2911-500 | Biotium | 1uL | EUR 485 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), 1mg/mL |
|||
| BNUM2911-50 | Biotium | 1uL | EUR 396 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Dilinoleyl DiI (Fast DiI, or 1, 1'-dilinoleyl-3, 3, 3', 3'-tetramethylindocarbocyanine perchlorate: (5mg) |
|||
| 60034 | Biotium | 5MG | EUR 316.8 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
5-(and-6)-Carboxyrhodamine 110-X, succinimidyl ester, hydrochloride (5(6)-CR 110-X, SE): (5mg) |
|||
| 90003 | Biotium | 5MG | EUR 368.4 |
|
Description: Minimum order quantity: 1 unit of 5MG |
|||
Recombinant Mouse EGF/ Epidermal Growth Factor Protein, Untagged, E.coli-5mg |
|||
| QP4008-5mg | EnQuireBio | 5mg | EUR 1393.2 |
Recombinant Human EGF/ Epidermal Growth Factor Protein, Untagged, E.coli-5mg |
|||
| QP5334-5mg | EnQuireBio | 5mg | EUR 1393.2 |
Recombinant Human GH1/ Growth hormone 1 Protein, Untagged, E.coli-5mg |
|||
| QP5354-5mg | EnQuireBio | 5mg | EUR 871.2 |
Recombinant Virus Parvovirus B19 VLP VP1 Protein, Untagged, E.coli-5mg |
|||
| QP12966-5000ug | EnQuireBio | 5mg | EUR 795.6 |
SingleStep Poly-HRP Anti-Mouse IgG (H+L) Secondary Antibody, HRP-5mg |
|||
| Q2AB1-5mg | EnQuireBio | 5mg | EUR 747.6 |
SingleStep Poly-HRP Anti-Rabbit IgG (H+L) Secondary Antibody, HRP-5mg |
|||
| Q2AB2-5mg | EnQuireBio | 5mg | EUR 747.6 |
Recombinant S. aureus E. coli ssPA/ Stringent starvation Protein, Untagged, E.coli-5mg |
|||
| QP5524-5mg | EnQuireBio | 5mg | EUR 3003.6 |
Nestin (Cancer Stem Cell Marker)(NES/2911), CF568 conjugate, 0.1mg/mL |
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| BNC682911-100 | Biotium | 1uL | EUR 192 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
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Nestin (Cancer Stem Cell Marker)(NES/2911), CF568 conjugate, 0.1mg/mL |
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| BNC682911-500 | Biotium | 1uL | EUR 532 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
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Nestin (Cancer Stem Cell Marker)(NES/2911), CF647 conjugate, 0.1mg/mL |
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| BNC472911-100 | Biotium | 1uL | EUR 192 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
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Nestin (Cancer Stem Cell Marker)(NES/2911), CF647 conjugate, 0.1mg/mL |
|||
| BNC472911-500 | Biotium | 1uL | EUR 532 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
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Nestin (Cancer Stem Cell Marker)(NES/2911), CF594 conjugate, 0.1mg/mL |
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| BNC942911-100 | Biotium | 1uL | EUR 192 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), CF594 conjugate, 0.1mg/mL |
|||
| BNC942911-500 | Biotium | 1uL | EUR 532 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), CF405S conjugate, 0.1mg/mL |
|||
| BNC042911-100 | Biotium | 1uL | EUR 192 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), CF405S conjugate, 0.1mg/mL |
|||
| BNC042911-500 | Biotium | 1uL | EUR 532 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), CF640R conjugate, 0.1mg/mL |
|||
| BNC402911-100 | Biotium | 1uL | EUR 192 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), CF640R conjugate, 0.1mg/mL |
|||
| BNC402911-500 | Biotium | 1uL | EUR 532 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), CF488A conjugate, 0.1mg/mL |
|||
| BNC882911-100 | Biotium | 1uL | EUR 192 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), CF488A conjugate, 0.1mg/mL |
|||
| BNC882911-500 | Biotium | 1uL | EUR 532 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), Biotin conjugate, 0.1mg/mL |
|||
| BNCB2911-100 | Biotium | 1uL | EUR 192 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Nestin (Cancer Stem Cell Marker)(NES/2911), Biotin conjugate, 0.1mg/mL |
|||
| BNCB2911-500 | Biotium | 1uL | EUR 532 |
|
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application |
|||
Active Nesfatin 1 (NES1) |
|||
| 4-APA242Mu01 | Cloud-Clone |
|
|
|
Description: Recombinant Mouse Nesfatin 1 expressed in: E.coli |
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Active Nesfatin 1 (NES1) |
|||
| 4-APA242Ra01 | Cloud-Clone |
|
|
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Description: Recombinant Rat Nesfatin 1 expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
|||
Active Nesfatin 1 (NES1) |
|||
| RPU54887-100ug | Biomatik Corporation | 100ug | EUR 1108.8 |
Active Nesfatin 1 (NES1) |
|||
| RPU54887-1mg | Biomatik Corporation | 1mg | EUR 4914 |
Active Nesfatin 1 (NES1) |
|||
| RPU54887-50ug | Biomatik Corporation | 50ug | EUR 891 |
Active Nesfatin 1 (NES1) |
|||
| RPU55513-100ug | Biomatik Corporation | 100ug | EUR 1211.1 |
Active Nesfatin 1 (NES1) |
|||
| RPU55513-1mg | Biomatik Corporation | 1mg | EUR 4773.6 |
Active Nesfatin 1 (NES1) |
|||
| RPU55513-50ug | Biomatik Corporation | 50ug | EUR 734.4 |
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| CEA242Ra-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 5552.14 |
|
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Rat Nesfatin 1 (NES1) in serum, plasma and other biological fluids. |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| CEA242Ra-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 562.42 |
|
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Rat Nesfatin 1 (NES1) in serum, plasma and other biological fluids. |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| CEA242Ra-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 752.02 |
|
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Rat Nesfatin 1 (NES1) in serum, plasma and other biological fluids. |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| CEA242Ra-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3024.07 |
|
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Rat Nesfatin 1 (NES1) in serum, plasma and other biological fluids. |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| 4-CEA242Ra | Cloud-Clone |
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Rat Nesfatin 1 (NES1) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| SEA242Ra-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 6934.44 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Nesfatin 1 (NES1). |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| SEA242Ra-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 676.25 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Nesfatin 1 (NES1). |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| SEA242Ra-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 914.64 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Nesfatin 1 (NES1). |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| SEA242Ra-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3755.88 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Nesfatin 1 (NES1). |
|||
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| 4-SEA242Ra | Cloud-Clone |
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Nesfatin 1 (NES1) in samples from n/a with no significant corss-reactivity with analogues from other species. |
|||
Rat Nesfatin 1(NES1)ELISA Kit |
|||
| QY-E10219 | Qayee Biotechnology | 96T | EUR 433.2 |
Rat Nesfatin 1(Nes-1)ELISA kit |
|||
| YLA0326RA-48T | Shanghai YL Biotech | 48T | EUR 465 |
Rat Nesfatin 1(Nes-1)ELISA kit |
|||
| YLA0326RA-96T | Shanghai YL Biotech | 96T | EUR 600 |
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| EKN51275-48T | Biomatik Corporation | 48T | EUR 424.76 |
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| EKN51275-5x96T | Biomatik Corporation | 5x96T | EUR 2882.3 |
Rat Nesfatin 1 (NES1) ELISA Kit |
|||
| EKN51275-96T | Biomatik Corporation | 96T | EUR 606.8 |
Additional progress of this method is dependent upon crossing disciplinary boundaries and complicated simulations of organic methods. Evolutionary methods biology (ESB) by the combination of strategies from evolutionary biology and methods biology goals to the understanding of the basic ideas of life in addition to the prediction of organic methods evolution.